Atomically Precise Gold Nanoclusters by Alternate Pumping Chromatography

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We just published an exciting open access work where we present a new, very efficient chromatographic process for producing highly defined nanomaterials. Specifically, we devised a special two-column process, alternate pumping, for obtaining small, atomically precise gold nanoclusters at high purity from synthesized mixtures. By utilization of anion exchange chromatography as established by our partners at LFG, we demonstrate the capability of alternate pumping to isolate a single cluster with 10 gold atoms (Au10), or two different larger clusters simultaneously (Au25 and Au29). Additionally, we successfully enriched trace amounts of Au18 and proposed a simple design procedure for utilizing columns with different retention behaviors. Discover the potential of preparative chromatography for the production of such high-quality nanoparticulate products that provide transformative possibilities in catalysis, sensing, and biomedicine.

Publication details:

Malvina Supper, Virignia Birner, Lukas Gromotka, Wolfgang Peukert, Malte Kaspereit:
Isolation and Purification of Single Gold Nanoclusters by Alternate Pumping Chromatography
Separations 10 (2023) 214.
ISSN: 2297-8739
DOI: 10.3390/separations10030214

The work was supported by the German Science Foundation (DFG) through the Collaborative Research Centre CRC 1411 “Design of Particulate Products”.